Expression of Desmogleins in Paget Cells of Mammary and Extramammary Paget's Disease.
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چکیده
منابع مشابه
Extramammary Paget Disease: Minimal Surgical Therapy
BACKGROUND Extramammary Paget disease (EMPD) is an uncommon malignant neoplasm affecting apocrine gland-bearing skin which usually occurs in the anogenital area of patients older than 50 years. Although Mohs micrographic surgery (MMS) is recommended for the treatment of EMPD, wide local excision has also been performed by many other surgeons including dermatosurgeons. However, the extent of an ...
متن کاملMammary and extramammary Paget’s disease
Mammary and extramammary Paget’s disease are uncommon intraepithelial adenocarcinomas. Both conditions have similar clinical features, which mimic inflammatory and infective diseases. Histological diagnostic confusion can arise between Paget’s disease and other neoplastic conditions aVecting the skin, with the most common diVerential diagnoses being malignant melanoma and atypical squamous dise...
متن کاملMammary and extramammary Paget's disease*
Paget's disease, described by Sir James Paget in 1874, is classified as mammary and extramammary. The mammary type is rare and often associated with intraductal cancer (93-100% of cases). It is more prevalent in postmenopausal women and it appears as an eczematoid, erythematous, moist or crusted lesion, with or without fine scaling, infiltration and inversion of the nipple. It must be distingui...
متن کاملMammary and extramammary Paget's disease.
Paget's disease is an intra-epidermal adenocarcinoma seen over the nipple/areola (mammary Paget's disease) or in extramammary body zones, such as the anogenital and perineal skin and the axilla. Mammary and extramammary Paget's disease share many common clinicopathological features but also show several differences, namely, with regard to pathogenesis and association with underlying malignancie...
متن کاملHistochemical Demonstration of Transglycosylases and Oxidative Enzymes in the Paget Cells of Extramammary Paget's Disease.
Although many histochemical investigations have been reported on the mucin in the cytoplasm of PAGET cells (LENNOX and PEARSE 1954, STRAUSS 1957, JOHNSON and HELWIG 1963, SASAI, AKIBA and TANAHASHI 1964), there are but few reports concerning an enzymohistochemistry in those cells (BRAUNFALCO and RATHJENS 1955, FANGER and BARKER 1959, STEIGLEDER and KAMEI 1963). In general, it is accepted that t...
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ژورنال
عنوان ژورنال: The Kurume Medical Journal
سال: 1997
ISSN: 0023-5679,1881-2090
DOI: 10.2739/kurumemedj.44.185